MAXIMUM STRENGTH Sam -e 400MG DAILY DOSE - 400mg of Sam e which not only supports mood and feeling of well-being, but also supports joint, liver, and brain function. It also promotes mental performance and helps with symptoms of anxiety. Sam e is also sometimes taken to help with anti-aging, fatigue, or difficulty with concentration. * PROMOTES BRAIN HEALTH: Supports cognitive function, and helps enhance energy levels & mood. SAMe is a key component for metabolism of neurotransmitters serotonin, norepinephrine, & dopamine. May help combat symptoms of anxiety. * S SUPERIOR HEALTH SAMe is blended and packaged in the U.S.A. from U.S. and imported ingredients.